Synthesis and Properties of Cleavable Quaternary Ammonium Compounds

Synthesis, Micellization and Hemolysis Evaluation of Biodegradable quaternary Ammonium Compounds

Surfactants have the special ability to interact with the lipid bilayer of cell membranes. The red blood cell is one of the most used cellular membrane models to study the mechanisms underlying surfactant – induced osmotic cell resistance.The aim of this study is the evaluation of the effect of the prepared surfactants on red blood cells (RBC) as a model for biological membranes. Also, in this ...

Interactions of Quaternary Ammonium Compounds and Proteins

A simple met.hod of titration with a cationic detergent has been developed which permits rapid estimation of the concentration of urinary protein with a minimum of manipulations and time. The method depends on the formation of an insoluble anion-cation complex between quaternary ammonium ions, hereinafter referred to as the cationic detergent, and proteins, in the present instance mainly human ...

The Electroreduction of Quaternary Ammonium Compounds

Quaternary Ammonium Compounds as Water Channel Blockers

From the Department of Physiology, Nijmegen Center for Molecular Life Sciences, Radboud University Nijmegen Medical Center, 6500 HB Nijmegen, Nijmegen, The Netherlands, the Max-Planck Institute for Biophysical Chemistry, Theoretical and Computational Biophysics Department, Am Fassberg, D-37077, Göttingen, Germany, and the Department of Chemistry, University of Edinburgh, Kings Buildings, West M...

[Quaternary ammonium compounds--new occupational hazards].

Quaternary ammonium compounds (QACs, quats) belong to organic ionic chemical agents which display unique properties of both surfactants and disinfectants. Their wide distribution in the work environment and also in private households brings about new occupational hazards. This paper reviews reports about the health effects of QACs. QACs could play a role of sensitizers and irritants to the skin...